Get the Mariners vs. White Sox prediction with odds, series recap, player props, parlay picks and best bets for this Tuesday MLB game. The Seattle Mariners (27-19) roll into the South Side looking to build momentum in Game 2 of their series against the struggling Chicago White Sox (14-34), who are mired in a five-game losing streak. First pitch is set for 7:40 p.m. ET from Guaranteed Rate Field, and the game will be broadcast on CHSN and ROOT Sports NW.
Seattle continues to find ways to win despite a long list of injured arms, while the White Sox have yet to find their identity in a season full of inconsistency. Chicago turns to Bryse Wilson (0-2, 4.09 ERA) to stop the bleeding. Seattle has not named a starter yet, but their bullpen has been up to the challenge all season.
Cal Raleigh and Julio Rodríguez have been red-hot for the M’s, while Chicago leans heavily on Miguel Vargas and Luis Robert Jr. for any spark on offense. Oddsmakers favor Seattle as -177 moneyline favorites, and the over/under is set at 8 runs.
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📺 Where To Watch Mariners vs. White Sox? (May 20, 2025)
- 📅 Date: Tuesday, May 20, 2025
- 🕢 Time: 7:40 p.m. ET
- 📍 Location: Guaranteed Rate Field, Chicago, IL
- 📺 Where to Watch: CHSN, ROOT Sports NW
- 📲 Stream: FuboTV (regional restrictions may apply)
💰 Betting Odds
| Team | Spread | Moneyline | Total |
| Seattle Mariners | -1.5 (-106) | -177 | O 8 (-124) |
| Chicago White Sox | +1.5 (-114) | +148 | U 8 (+103) |
🔥 Pitching Matchup
| Pitcher | Team | W-L | ERA | WHIP | Last Start |
| Bryse Wilson | White Sox | 0-2 | 4.09 | 1.41 | 5.0 IP, 3 ER vs CLE |
| TBD | Mariners | – | – | – | Bullpen likely start |
Seattle’s pitching situation remains unclear, with multiple starters on the IL. Expect a bullpen game or a spot start. Bryse Wilson will look to pitch deeper into the game after a decent showing in his last outing.
📊 Team Stats & Trends
| Category | Mariners (Rank) | White Sox (Rank) |
| Runs Per Game | 4.8 (11th) | 3.3 (28th) |
| Team ERA | 3.78 (14th) | 4.25 (21st) |
| Home Runs | 63 (6th) | 37 (27th) |
| Batting Average | .238 (21st) | .216 (29th) |
| Strikeouts/Game | 8.9 (22nd) | 8.4 (20th) |
🔑 Key Players to Watch
⚓ Seattle Mariners
- Cal Raleigh – 15 HR, 32 RBI, .241 AVG
- Julio Rodríguez – .235 AVG, 8 HR, 17 BB, 7-game hit streak
- Jorge Polanco – .314 AVG, 10 HR, .619 SLG
⚾ Chicago White Sox
- Miguel Vargas – 6 HR, 21 RBI, .299 AVG
- Luis Robert Jr. – 5 HR, .186 AVG, 21 BB
- Chase Meidroth – .286 AVG, consistent OBP threat
🚑 Injury Report
Seattle Mariners
- Luke Raley (Side) – 10-Day IL
- Bryce Miller (Elbow) – 15-Day IL
- George Kirby (Shoulder) – 15-Day IL
- Logan Gilbert (Forearm) – 15-Day IL
Chicago White Sox
- Andrew Benintendi (Calf) – 10-Day IL
- Korey Lee (Ankle) – 10-Day IL
- Mike Tauchman (Hamstring) – 10-Day IL
- Martín Pérez (Forearm) – 60-Day IL
🧢 Player Props
| Player | Hits O/U | Total Bases O/U | RBI O/U |
| Cal Raleigh | 0.5 (-185) | 1.5 (+105) | 0.5 (+100) |
| Julio Rodríguez | 1.5 (+160) | 1.5 (-115) | 0.5 (+120) |
| Jorge Polanco | 0.5 (-210) | 1.5 (+115) | 0.5 (+160) |
| Miguel Vargas | 0.5 (-150) | 0.5 (-155) | 0.5 (+245) |
🔁 Recent Form (Last 10 Games)
| Team | Record | Runs/Game | Team ERA | HRs |
| Mariners | 5-5 | 3.6 | 3.82 | 12 |
| White Sox | 4-6 | 3.0 | 4.24 | 11 |
🧠 Final ClutchBuzz Mariners vs. White Sox Prediction
Seattle’s offense should have the edge, even without a confirmed starter. The White Sox are simply not generating enough scoring chances, while the Mariners continue to win with power and timely hitting. Bryse Wilson will need a near-flawless start to give Chicago a chance.
✅ Score Prediction: Mariners 5, White Sox 4
💣 Total Prediction: Over 8 Runs
💵 Best Bets: Mariners -1.5, Julio Rodríguez 2+ total bases
🎰 Same Game Parlay (SGP):
- Mariners ML
- Cal Raleigh RBI
- Over 7.5 Runs
🧮 Estimated Odds: +450
