Get odds, pitcher matchup, player props, betting trends, and a bold same-game parlay pick for Monday’s Cubs vs. Giants.
Wrigley Field will be rocking on Monday night as the Chicago Cubs (21-14) host the San Francisco Giants (22-13) to open a highly anticipated NL series. The Cubs send Matthew Boyd to the mound to face off with Landen Roupp, as Chicago aims to keep their offensive surge alive behind stars like Kyle Tucker and Pete Crow-Armstrong.
Still, don’t count out the Giants—Willy Adames is coming off a two-homer performance, and Wilmer Flores leads San Francisco with 31 RBIs on the season. First pitch is set for 7:40 p.m. ET on MARQ and NBCS-BA.
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📺 Where To Watch Cubs vs. Giants? (May 5, 2025)
| Detail | Info |
| Date | Monday, May 5, 2025 |
| Time | 7:40 p.m. ET |
| TV | MARQ, NBCS-BA |
| Location | Wrigley Field (Chicago, IL) |
💰 Betting Odds
| Type | Cubs | Giants |
| Moneyline | -148 | +125 |
| Run Line | -1.5 (+144) | +1.5 (-173) |
| Total | O 7.5 (-113) | U 7.5 (-106) |
💡 Prediction: Cubs 5, Giants 4
✅ Pick: Over 7.5 Runs
⚾ Pitching Matchup
| Team | Pitcher | Stats |
| Cubs | Matthew Boyd | 2-2, 2.70 ERA, 30 K in 33.1 IP |
| Giants | Landen Roupp | 2-2, ERA TBD, 6th start |
🏥 Injury Report
Cubs:
- Shota Imanaga (day-to-day, leg)
- Tyson Miller (15-Day IL, hip)
- Ryan Brasier (15-Day IL, hip)
- Eli Morgan (15-Day IL, elbow)
- Justin Steele (60-Day IL, elbow)
- Javier Assad (60-Day IL, oblique)
Giants:
- Casey Schmitt (10-Day IL, side)
- Tyler Fitzgerald (10-Day IL, ribs)
- Thomas Murphy (60-Day IL, back)
- Jerar Encarnación (60-Day IL, finger)
🔑 Key Players to Watch
Cubs:
- Kyle Tucker (.292 AVG, 9 HR, 30 RBI) – 4-game hit streak
- Pete Crow-Armstrong (9 HR, 26 RBI) – Power threat
- Carson Kelly (.368 AVG, 7 HR) – .807 SLG, red-hot bat
- Ian Happ (.286 AVG, .373 OBP) – 6-game hit streak
Giants:
- Wilmer Flores (7 HR, 31 RBI) – Team RBI leader
- Willy Adames – Coming off a 2-HR game
- Jung Hoo Lee (.305 AVG) – Contact specialist
- Matt Chapman (7 HR) – Grand slam hero last week
🔥 Team Trends
| Stat | Cubs | Giants |
| Record (L10) | 6-4 | 6-4 |
| Runs/Game | 5.2 | 4.1 |
| HR (L10 games) | 15 | 11 |
| Team ERA (L10 games) | 2.53 | 3.17 |
🎯 Player Prop Bets
Cubs:
| Player | Hits O/U | Total Bases O/U | RBI O/U |
| Kyle Tucker | 0.5 (-185) | 0.5 (-190) | 0.5 (+180) |
| Pete Crow-Armstrong | 0.5 (-180) | 0.5 (-185) | 0.5 (+185) |
| Carson Kelly | 0.5 (-170) | 0.5 (-175) | 0.5 (+160) |
Giants:
| Player | Hits O/U | Total Bases O/U | RBI O/U |
| Willy Adames | 0.5 (-155) | 0.5 (-155) | 0.5 (+225) |
| Matt Chapman | 0.5 (-165) | 0.5 (-165) | 0.5 (+160) |
| Wilmer Flores | 0.5 (-150) | 0.5 (-150) | 0.5 (+210) |
🔁 Same Game Parlay (SGP)
| Leg | Pick | Odds |
| Cubs ML | Cubs to win at home | -148 |
| Kyle Tucker RBI | Tucker to drive in at least 1 run | +145 |
| Over 7.5 Runs | Total runs scored in the game | -113 |
| Pete Crow-Armstrong HR | Crow-Armstrong to hit a home run | +185 |
🧪 Parlay Odds (Estimated): +1100
🧠 Final ClutchBuzz Cubs vs. Giants Prediction
The Cubs are hot offensively and send a reliable arm to the mound in Matthew Boyd, while the Giants are coming in with momentum after a power-packed series capped by a Willy Adames show. Still, Chicago’s lineup is deeper and more consistent right now, especially with Carson Kelly and Ian Happ red-hot. Expect a tight game early before the Cubs pull away late.
Cubs 5, Giants 4 — OVER 7.5 hits. Cubs cover the -1.5 run line.
