Get the Cubs vs. Mets prediction with odds, series recap, player props, parlay picks and best bets for this Tuesday MLB game.
The Chicago Cubs (88–68) and New York Mets (80–76) both enter Tuesday night’s matchup at Wrigley Field looking to snap losing streaks.
Chicago has dropped four straight, while New York has fallen in two in a row. With playoff races tightening, every game counts, and this one has the feel of October.
First pitch is set for 7:40 p.m. ET on TBS, MARQ, and SNY.
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📺 Where To Watch Cubs vs. Mets? (September 22, 2025)
| Matchup | New York Mets vs. Chicago Cubs |
| When | Tuesday, Sept. 23, 2025 – 7:40 PM ET |
| Where | Wrigley Field – Chicago, IL |
| TV | TBS, MARQ, SNY |
| Live Stream | Fubo (Sign up here) |
| Tickets | Available via Vivid Seats |
💰 Betting Odds
| Team | Spread | Moneyline | Total (O/U) |
| Cubs | -1.5 (+172) | -120 | O 7.5 (-110) |
| Mets | +1.5 (-205) | -100 | U 7.5 (-110) |
- ATS Prediction: Mets +1.5
- Total Prediction: Over 7.5
- Moneyline Prediction: Cubs -120
⚾ Pitching Matchup
Cubs Starter – Cade Horton (RHP)
- Record: 11-4
- ERA: 2.66
- WHIP: 1.10
- SO/9: 7.4
- BAA: .220
🟢 Recent Form (last 5 starts):
- 28.1 IP, 3 ER allowed, 25 K – pure dominance.
- Held opponents scoreless in 2 of the last 5 outings.
Mets Starter – David Peterson (LHP)
- Record: 9-6
- ERA: 3.98
- WHIP: 1.33
- SO/9: 8.0
- BAA: .254
🔴 Recent Form (last 5 starts):
- 24 IP, 23 ER allowed, ERA near 9.00.
- Gave up 6 ER to San Diego in the last outing.
Edge: Cubs. Horton is rolling, while Peterson has been shaky.
📊 Team Hitting Trends
Cubs (Last 10 Games)
- AVG: .254
- HR: 13
- XBH: 33
- Runs/Game: 4.1
- Hot Bat: Nico Hoerner (.366, 2B, 3B, 3 BB)
Mets (Last 10 Games)
- AVG: .252
- HR: 16
- XBH: 29
- Runs/Game: 4.3
- Hot Bat: Juan Soto (.308/.378/.590, 3 HR)
📋 Key Injuries
Cubs
- Kyle Tucker (Calf) – IL
- Justin Steele (Elbow) – 60-Day IL
- Owen Caissie (Concussion) – IL
- Miguel Amaya (Ankle) – IL
Mets
- Jesse Winker (Back) – 60-Day IL
- Griffin Canning (Achilles) – 60-Day IL
- Frankie Montás (Elbow) – 60-Day IL
- Tylor Megill (Elbow) – 60-Day IL
- Multiple bullpen arms sidelined (Minter, Nunez, Smith).
Impact: Mets’ pitching depth is severely tested.
🔑 Key Players to Watch
Chicago Cubs
- Nico Hoerner: .299 AVG, 59 RBI, team sparkplug.
- Seiya Suzuki: 27 HR, 91 RBI, power bat in middle of order.
- Cade Horton: 2.66 ERA, anchors one of MLB’s best rotations.
New York Mets
- Juan Soto: 42 HR, .590 SLG, MVP-caliber season.
- Francisco Lindor: 28 HR, 34 doubles, leader in clutch spots.
- Pete Alonso: .274 AVG, 122 RBI, elite run producer.
🔒 Best Prop Bets
| Bet | Line | Pick |
| Cade Horton Strikeouts | 6.5 | Over |
| Juan Soto HR | +350 | Yes |
| Total Runs | 7.5 | Over |
🧾 Same-Game Parlay (SGP)
| Leg | Pick | Odds* |
| Cubs ML | -120 | |
| Over 7.5 Runs | -110 | |
| Juan Soto HR | +350 |
Parlay Payout: +650 (Bet $100 → Win $650)
*Approximate combined odds.
🔮 Final ClutchBuzz Prediction
The Mets have the power bats to hang around, but the pitching matchup is too lopsided to ignore. Cade Horton is on a roll, while David Peterson is trending the wrong way. Expect Soto and Lindor to get theirs, but the Cubs’ lineup should capitalize against a struggling Mets starter.
Final Score: Cubs 5 – Mets 3
- Best Bet: Cubs ML (-120)
- Over/Under: Over 7.5 Runs
- Prop Play: Horton Over 6.5 Ks
