Find the Padres vs. Cubs prediction, odds, player props and same-game parlay picks here. After dropping bombs on the Dodgers, Pete Crow-Armstrong leads the Cubs into a heavyweight clash with the red-hot San Diego Padres. First pitch goes down at 9:40 p.m. ET from PETCO, where two sneaky offenses meet under SoCal skies.
The Padres (13-3) have been dominant early — winners in 9 of their last 10 — while the Cubs (11-7) continue to lead MLB in runs scored and bring their power bats to the West Coast.
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📊 Where To Watch Padres vs. Cubs? (April 14, 2025)
📍 Venue: PETCO Park, San Diego, CA
🕘 Time: 9:40 p.m. ET
📺 Watch: SDPA, MARQ | Stream: Fubo, MLB.tv
💸 Padres vs. Cubs Betting Odds
| Market | Padres | Cubs |
| 💰 Moneyline | -164 (Favored) | +138 (Underdog) |
| 🧱 Run Line | -1.5 (+134) | +1.5 (-161) |
| 📊 Total | Over 7.5 (-103) | Under 7.5 (-117) |
🔍 Matchup Overview
| Team | Record | Last 10 | Run Diff | Team BA | ERA | HRs | Strikeouts/Game |
| Padres | 13-3 | 7-3 | +34 | .283 (1st) | 2.68 (2nd) | 15 | 6.4 (Fewest) |
| Cubs | 11-7 | 7-3 | +21 | .256 (6th) | 4.02 (18th) | 25 | 8.1 (23rd) |
🧢 Starting Pitchers
| Pitcher | Team | W-L | ERA | K | WHIP | Last Start |
| Dylan Cease | Padres | 1-1 | 7.98 | 18 | 1.71 | Allowed 5 ER in 5 IP vs. ARI |
| Jameson Taillon | Cubs | 1-1 | 6.06 | 14 | 1.53 | 6 IP, 3 ER, 6 K vs. PIT |
🧨 Key Hitters to Watch
🔵 Padres
| Player | AVG | HR | RBI | OPS | Note |
| Fernando Tatis Jr. | .351 | 4 | 11 | .985 | Hit in 3 straight, 3 HR last 5 |
| Manny Machado | .317 | 1 | 9 | .860 | 7 doubles, solid gap power |
| Xander Bogaerts | .304 | 0 | 5 | .778 | 5 doubles, excellent OBP (.385) |
🔴 Cubs
| Player | AVG | HR | RBI | OPS | Note |
| Kyle Tucker | .324 | 5 | 18 | .989 | Leads team in HR & RBI |
| Carson Kelly | .417 | 4 | 12 | 1.245 | Red-hot, ranks 13th in MLB RBI |
| Michael Busch | .315 | 3 | 11 | .970 | Multiple XBHs in last 5 games |
🩺 Injury Report
| Team | Player | Injury | Status |
| Padres | Yu Darvish | Elbow | 15-Day IL |
| Joe Musgrove | Elbow | 60-Day IL | |
| Cubs | Justin Steele | Elbow | 15-Day IL |
| Ryan Brasier | Hip | 15-Day IL |
💸 Padres vs. Cubs Prop Bets (Best Value Picks)
| 🧍 Player | 💥 Prop Type | 💰 Odds | 📈 Bet Insight |
| Fernando Tatis Jr. | Over 1.5 Total Bases | -110 | Has 3 HR in his last 5 games; hitting .351 and slugging .596. 🔥 |
| Kyle Tucker | Over 0.5 RBI | +125 | Leads the Cubs with 18 RBI. Cubs averaging 6.6 runs over last 10. |
| Carson Kelly | Hit + Run + RBI o2.5 | +140 | Slashing .417 with power; multi-hit games in 3 of last 5. |
| Michael Busch | Over 1.5 Hits + Walks | +135 | Reaching base at a .375 clip; Cubs OBP machine near the top of order. |
| Manny Machado | To Hit a Double | +280 | Has 7 doubles already; facing a hittable Taillon fastball-heavy profile. |
🔗 Same Game Parlay (SGP)
💰 +525 Payout Parlay (FanDuel / DK / MGM):
- ✅ Padres ML (-164)
- ✅ Over 7.5 Total Runs (-103)
- ✅ Fernando Tatis Jr. Over 1.5 Total Bases (-110)
- ✅ Kyle Tucker Anytime RBI (+125)
🔎 Why it works: Padres are red-hot offensively, and Cubs have power to keep it close. Tatis is crushing righties, and Tucker is seeing the ball well with men on.
📊 Prop Trends to Note
- Tatis Jr.: Hit prop cashed in 8 of last 10 games
- Kelly: Has reached base in 13 of 15 games played
- Cubs: 7-3 to the over in last 10 games
- Padres: 5-1 ATS in last 6 games as favorites
🔮 Prediction & Final Take
San Diego is playing near-flawless baseball at home and gets a Cubs team coming off a big win but with shaky arms on the bump. Expect fireworks early — both lineups are red-hot — but the Padres bullpen gives them the edge late.
Final Score Prediction:
🟦 Padres 6 – 🟥 Cubs 5
Pick: Over 7.5 Runs ✅ | Padres ML ✅
